Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility.
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چکیده
منابع مشابه
Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility.
Polymorphisms in many xenobiotic metabolizing enzymes occur leading to variation in the level of enzyme expression in vivo. Enzymes showing such polymorphisms include the cytochrome P450 enzymes CYP1A1, CYP1A2, CYP2A6, CYP2D6, and CYP2E1 and the phase two metabolism enzymes glutathione S-transferase MI (GSTMI) and arylamine N-acetyltransferase 2 (NAT2). In the past, these polymorphisms have bee...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1994
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.94102s955